However, there are no clinical data to support the efficacy of these cleanses. In fact, some dietary supplements can actually cause harm to the liver by leading to drug-induced injury and should thus be used with caution. “It’s one of my favorites when I’m doing a detox because it’s really high in amino acids like glycine, which actually supports liver detox,” he says. “I add lots of vegetables and even green apples.” Find out more about the only cleanse diet that nutritionists approve of. One process by which the body eliminates toxins is enzymatic detoxification in the liver. A reliable biomarker for exposure to toxic chemicals is urinary D-glucaric acid. Such exposures induce the glucuronic acid enzymatic pathway and production of D-glucaric acid, thus urinary D-glucaric acid is an indirect byproduct of chemical exposure and phase I detoxification reactions.

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